Research Article Fucoidan and Fucoxanthin Ameliorate Cardiac Function of Aging Canine
Các tập tin
Ngày
2017-10-15
Tác giả
Chih-Hung Tsai
Phan Nam
Yen-Chang Lin
Tên Tạp chí
Tạp chí ISSN
Nhan đề tập
Nhà xuất bản
Trường Đại học Nguyễn Tất Thành (Tạp chí Khoa học công nghệ NTT)
Giấy phép
Tóm tắt
In this study, fucoidan in combination with fucoxanthin were used to enhance the impaired cardiac systolic and diastolic function in aging canine model. Materials and Methods: Aging canines were fed with fucoidan (125 mg kgG1) and fucoxanthin (125 mg kgG1) for 3 months. Echo cardiography was used to compute Tei index and related parameter such as E / E`, E` / A` and isovolumetric relaxation time (IVRT), isovolumetric contraction time (IVCT) was calculated using the Doppler model. T-Test was used to compare echo parameters. Data were displayed as Mean±SD. SPSS was used for statistical analysis. Results: IVRT and IVCT were shortened with 15.78±3.71 and 24.53±6.71%, respectively after fucoidan and fucoxanthin treatment, suggested that these two phytochemical compounds have cardioprotective effects in aging canine subjects with degenerative valve disease. Conclusion: After 3 consecutive months of Fucoidan and fucoxanthin usage, the cardiac function of aging canine was improved. Fucoidan and fucoxanthin may be considered as a potential treatment or supplement to aging canine subjects with abnormality in cardiac function.
Mô tả
9 tr.
Từ khóa
Fucoidan , Fucoxanthin , Aging canine