Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria
Ngày
2025-10
Tác giả
Amoako, Daniel Gyamfi
Bester, Linda
Tên Tạp chí
Tạp chí ISSN
Nhan đề tập
Nhà xuất bản
MDPI
Giấy phép
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Tóm tắt
In the ever-evolving battle against antimicrobial resistance (AMR), our understanding of the genomic landscape of bacteria and their mechanisms of evolution has become pivotal. In bacteria, resistance to antibiotics is determined by genetic factors such as chromosomes, plasmids or other movable genetic elements. Although antimicrobial resistance genes (ARGs) typically exhibit significant sequence variability, such as the impact of different concentrations of antibiotics on their genomic dynamics, the impact of this diversity on AMR is still unclear. Therefore, understanding the dynamic changes and mobilization of antibiotic resistance genes in humans, animals, plants and environmental microorganisms through genomics and metagenomics methods is crucial.
This Special Issue seeks to foster a comprehensive understanding of the genetic underpinnings of bacterial antimicrobial resistance and the evolutionary dynamics that underlie these adaptations.
Mô tả
200 p.
Từ khóa
antimicrobial resistance mechanism , mobile genetic element , horizontal gene transfer , resistome , evolution , molecular phylogenetics , genomics , bioinformatics analysis , next-generation sequencing