Evaluation of Antineoplastic Activity of Aloe vera latex extract on Human Hepatic Cancer Cell Line
Ngày
2023
Tác giả
Vo, Thanh Sang
Mach, Bao Ngoc
Tên Tạp chí
Tạp chí ISSN
Nhan đề tập
Nhà xuất bản
Nguyen Tat Thanh University
Giấy phép
Tóm tắt
Liver cancer is one of the most common fatal types of cancer over the world. Conventional cancer treatments such as surgery, chemotherapy and radiation therapy are costly and requires long-term commitment to be effective, which eventually leads to financial burden and suffering of patients and their families. Natural extracts originated from plants have been studied and exploited as pharmaceutical products or functional products supporting cancer treatments for years. The purpose of this study is to evaluate the antineoplastic activity of Aloe vera on Huh-7 cell line. The results showed that dimethyl sulfoxide extract from Aloe vera latex had cytotoxicity on Huh-7 cell line after (24-48) h of treatment with IC50 value at (160.72 ± 2.95) µg/mL and (156.41 ± 1.30) µg/mL respectively. Besides, the extract also inhibited the migration of cancer cells in (24-48) h treatment at minimum concentration of 100 µg/mL. Hence, Aloe vera latex extract is considered a potential anticancer agent against the proliferation of hepatic cancer cell.
Mô tả
6 p.
Từ khóa
Natural extracts , Anticancer agent , Huh-7 cell line , Aloe vera , Liver cancer , Ung thư Gan , Nha đam , Dược liệu
Trích dẫn
Nguyen Tat Thanh University. (2024). Journal of Science and Technology - NTTU, Volume 5, Issue 3. ISSN 2615-9015.