Evaluation of Antineoplastic Activity of Aloe vera latex extract on Human Hepatic Cancer Cell Line

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dc.contributor.authorVo, Thanh Sang
dc.contributor.authorMach, Bao Ngoc
dc.date.accessioned2024-08-23T06:37:44Z
dc.date.available2024-08-23T06:37:44Z
dc.date.issued2023
dc.description6 p.
dc.description.abstractLiver cancer is one of the most common fatal types of cancer over the world. Conventional cancer treatments such as surgery, chemotherapy and radiation therapy are costly and requires long-term commitment to be effective, which eventually leads to financial burden and suffering of patients and their families. Natural extracts originated from plants have been studied and exploited as pharmaceutical products or functional products supporting cancer treatments for years. The purpose of this study is to evaluate the antineoplastic activity of Aloe vera on Huh-7 cell line. The results showed that dimethyl sulfoxide extract from Aloe vera latex had cytotoxicity on Huh-7 cell line after (24-48) h of treatment with IC50 value at (160.72 ± 2.95) µg/mL and (156.41 ± 1.30) µg/mL respectively. Besides, the extract also inhibited the migration of cancer cells in (24-48) h treatment at minimum concentration of 100 µg/mL. Hence, Aloe vera latex extract is considered a potential anticancer agent against the proliferation of hepatic cancer cell.
dc.identifier.citationNguyen Tat Thanh University. (2024). Journal of Science and Technology - NTTU, Volume 5, Issue 3. ISSN 2615-9015.
dc.identifier.issn2615-9015
dc.identifier.urihttps://oerrepository.ntt.edu.vn/handle/298300331/191
dc.language.isovi_VN
dc.publisherNguyen Tat Thanh University
dc.relation.ispartofseriesJournal of Science and Technology - NTTU; Vol.5, No. 3
dc.subjectNatural extracts
dc.subjectAnticancer agent
dc.subjectHuh-7 cell line
dc.subjectAloe vera
dc.subjectLiver cancer
dc.subjectUng thư Gan
dc.subjectNha đam
dc.subjectDược liệu
dc.titleEvaluation of Antineoplastic Activity of Aloe vera latex extract on Human Hepatic Cancer Cell Line
dc.typeArticle
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