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Đang hiển thị 1 - 5 trong tổng số 90
- Tài liệuAdvances in Infant and Pediatric Feeding and Nutrition(MDPI, 2025) Foster, JannThis Reprint covers a broad spectrum of topics, ranging from the epigenetic effects of human milk on the ongoing neurodevelopment of infants and children, the impact of milk oligosaccharides, the effect of maternal fish consumption, and the use of bovine colostrum or infant formula from hydrolyzed whey protein to the validation of an instrument for evaluating parental feeding behaviors, breastfeeding, and childhood caries. The articles herein provide novel insights into the complex nature of infant feeding and nutrition and deepen our understanding of issues related to feeding and nutrition, paving the way for practical applications and future research.
- Tài liệuAdvances in Molecular Biology Methods in Hepatology Research(MDPI, 2025-10) Nair, Dileep G.; Weiskirchen, RalfRecent advances in molecular biology methods have profound implications for deciphering the complexities of hepatology research, specifically in understanding liver function, disease development, and novel therapies. The integration of genomic and proteomic technologies such as Next-Generation Sequencing (NGS), single-cell sequencing, CRISPR-Cas9, sensitive mass spectrometry, high-throughput proteomics, and epigenetic studies allow for a more comprehensive analysis of the liver's genomic landscape. These technologies enable scientists to understand the molecular pathways involved in liver injury, fibrosis, and regeneration. In addition to advances in genomic techniques, the development of advanced hepatic in vivo models and liver tissue engineering, utilizing technologies such as CRISPR-Cas9, places a clear emphasis on creating humanized organoid models. These molecular innovations, like hepatic organoids, are scalable for high-throughput screening and can replicate complex cellular interactions, providing further insights into the mechanisms underlying liver diseases such as metabolic dysfunction-associated steatotic liver disease (MASLD), hepatitis, and liver fibrosis. By creating patient-derived organoids, researchers can personalize disease models and uncover individualized disease mechanisms and precision therapeutics. Overall, these advancements in molecular biology have propelled hepatology research to the next level, offering additional opportunities for efficient diagnosis, treatment, and prevention strategies for hepatic diseases.
- Tài liệu20th Anniversary of Pharmaceuticals: Advances in Pathophysiology, Pharmacology and Neuroprotection in Glaucoma(MDPI, 2025-10) Sharif, Najam A.The Special Issue Reprint encompassing peer-reviewed articles on glaucoma and neuroprotection is timely, as the constellation of eye diseases is ever-increasing as the world’s population ages. The aim of the Special Issue was to capture some leading aspects of on-going research into pathophysiology, genetics and current and future therapeutic treatment options to mitigate the signs and symptoms of these potentially blinding disorders, especially open-angle and normotensive glaucoma that affect millions worldwide. I hope that this collection of original research and review articles will spur further interest in these elements in the academic arena and in the biopharmaceutical industries.
- Tài liệuAdvanced Clinical Technologies in Treating Neurosurgical Diseases(MDPI, 2025-10) Servadei, Franco; Arnautovic, Kenan; Stefini, RobertoIn this Special Issue of Brain Sciences, we offer a glimpse into the future of neurosurgery. Neurosurgery and clinical neuroscience are increasingly shaped by technological innovation, the refinement of therapeutic protocols, and the development of novel rehabilitative paradigms. Advances include adoption of 3D navigation to enhance surgical outcomes, the application of virtual iMRI, refinements in fluorescence-guided surgery, the emergence of new intraoperative neuroimaging techniques, robotic-assisted surgery, and the use of nanotechnology. Looking ahead, the field will further integrate biomechanical engineering, computational neuroscience, advanced simulation-based education, and translational oncology. These emerging technologies will continue to transform the paradigms of diagnosis, intervention, and rehabilitation in neurosurgery.
- Tài liệuMolecular Pharmacology and Interventions in Cardiovascular Disease(MDPI, 2025-10) Zabielska-Kaczorowska, MagdalenaThis Special Issue addresses researchers, physicians, and professionals involved in cardiovascular medicine, pharmacology, and biomedical research. The objective is to aggregate and promote the latest research findings, innovative methodologies, and therapeutic strategies concerning molecular mechanisms and therapies in cardiovascular diseases. By fostering collaboration among these diverse groups, this Special Issue aims to enhance understanding and ultimately improve patient outcomes. These contributions provide valuable insights that can influence future research and clinical practices.